What enzyme is known as the gluer?
What enzyme is known as the gluer?
DNA ligase
What is the role of DNA ligase during DNA replication?
DNA ligases play an essential role in maintaining genomic integrity by joining breaks in the phosphodiester backbone of DNA that occur during replication and recombination, and as a consequence of DNA damage and its repair.
What enzyme stabilizes the single strands of DNA in the replication fork?
Helicases
Which enzyme is responsible for adding nucleotides?
DNA polymerases
Which enzyme adds nucleotides to the 3 end of a primer?
DNA polymerase
What is the structural difference between the 3 and 5 end of a DNA strand?
The 3′ and 5′ ends have different chemical structures. The 5′ end is “capped” by a phosphate group, and the 3′ end is “capped” by a hydroxyl group.
What if DNA was parallel?
If the DNA strand was parallel, replication would not be possible. The nucleotides would not be complementary to each other and, as a result, would not pair in a genetic molecule. Therefore, the DNA being antiparallel is the only way replication and life could occur. The two strands of DNA are antiparallel.
Why is DNA antiparallel in arrangement?
DNA double helix is in opposite directions because of the opposite orientation of the sugar molecule in them. This antiparallel arrangement allows base pairs to complement one another. Therefore, antiparallel DNA is structurally more stable than parallel DNA. Anti-parallel stands allow the formation of hydrogen bonds.
Can DNA be parallel?
In nature, DNA and RNA exist in an antiparallel orientation, stabilized by Watson–Crick base pairs. However, in some cases, nucleic acid fragments with specific nucleotide sequences can adopt a parallel orientation involving non‐canonical base pairing.
Are the 2 strands of DNA identical?
Before a cell divides, its DNA is replicated (duplicated.) If the two strands of a DNA molecule are separated, each can be used as a pattern or template to produce a complementary strand. Each template and its new complement together then form a new DNA double helix, identical to the original.