Why is it important for eukaryotic DNA to have multiple origins of replication?
Why is it important for eukaryotic DNA to have multiple origins of replication?
Unlike prokaryotes, eukaryotic chromosomes often have multiple origins of replication. Considering the size of eukaryotic chromosomes, this is necessary to finish complete replication in a timely manner. Each of these origins defines a replicon, or the stretch of the DNA that is replicated from a particular origin.
Why there are multiple Ori sites in prokaryotes than one in eukaryotes?
Eukaryotic chromosomes are also much larger than their bacterial counterparts, raising the need for initiating DNA synthesis from many origins simultaneously to ensure timely replication of the entire genome.
Why do multiple replication bubbles form during DNA replication?
A replication bubble is an unwound and open region of DNA where DNA replication occurs. Bubbles are created when the enzyme helicase separates the two strands of DNA so that they can be replicated. DNA polymerase is an enzyme that adds complementary base pairs to create new partner strands for the original DNA strands.
What makes DNA replication so accurate?
The cell has multiple mechanisms to ensure the accuracy of DNA replication. The first mechanism is the use of a faithful polymerase enzyme that can accurately copy long stretches of DNA. The second mechanism would be for the polymerase to catch its own mistakes and correct them. DNA is double-stranded.
What is the result of normal DNA replication quizlet?
The outcome of DNA replication is two DNA nearly identical DNA double helix molecules. Each DNA is made up of one DNA strand from the original DNA and a newly created strand.
Why replication is called Semiconservative?
Semiconservative replication derives its name from the fact that this mechanism of transcription was one of three models originally proposed for DNA replication: Semiconservative replication would produce two copies that each contained one of the original strands of DNA and one new strand.
What is meant by Semiconservative DNA replication?
: relating to or being genetic replication in which a double-stranded molecule of nucleic acid separates into two single strands each of which serves as a template for the formation of a complementary strand that together with the template forms a complete molecule.
How many stages are there in DNA replication?
three